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A Breakthrough Ingredient

In Joint Care Research

Why Collagen Type II?

Scientifically Tested & Proven!

Clinical studies showed that Collagen Type II outperformed the glucosamine/chondroitin combination in supporting joint health and mobility.

Source: Crowley et al(2009). Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial. International Journal of Medical Sciences.

1. Glucosamine Sulphate (Plant-based)

Glucosamine Sulphate is a compound found naturally in the cartilage matrix and synovial fluid. It acts as a lubricant and keeps the joins moving smoothly. Taking Glucosamine Sulphate daily may help to promote healthy joint cartilage.

2. Chondroitin Sulphate

Chondroitin Sulphate is part of the structural components of joint cartilage and facilitates the entry of Glucosamine into joints. Via supplementation, it may help to promote healthy joint cartilage by absorbing fluid and promoting elasticity.

3. Hyaluronic Acidic

Hyaluronic Acid is a gel-like substance. The highest concentration can be found in connective tissues such as skin and cartilage. It may promote healthy joints via lubrication and shock absorption in the joints.

4. Vitamin D

Vitamin D helps the body absorb calcium to promote strong and healthy bones.

5. MSM (methylsufonylmethane)

MSM (methylsufonylmethane) is a natural form of organic sulfur found within the body. It supports joint flexibility and strength. MSM has been widely used for the maintenance of healthy joints.

6. Boswellia Serrata

BosPure® Boswellia (Boswellia Serrata, AKBA) is a patented Boswellia formula with one of nature's oldest and most powerful bioactive compound. It may assist in the maintenance of healthy joints. Clinical studies show that it is able to support mobility in 7 days.

7. Bio-2

Bio-2 is a Piperine extract formula that can help increase the bio-availability and absorption of Boswellia Serrata and other nutrients.

Full ingredient list: Vitamin D, Vitamin C (Ascorbic Acid), Manganese (Manganese Sulfate, Glucosamine Sulfate (Plant-based), Collagen Type 2 (from Protein Complex), Chondroitin Sulfate, (from Collagen Type 2 Complex), MSM, BosPure^®  (Boswellia Serrate), Hyaluronic Acid (from Collagen Type 2), Bio-2 (Piperine Extract).

• Jittery Joint
• Creaking Joint
• Stiffness
• Discomfort
• Inflexibility
• Weakness

• Promotes healthy knees, hands, shoulders, feet, hips, and spine
• Promotes healthy joint cartilage
• Promotes lubrication of healthy joints
• Assists with joint creaking
  
• Assists with joint flexibility and mobility

Direction of Use: For adults, take 2 capsules daily. Consume after meals.

Storage: Store in a cool and dry place. Once protection seal is opened, keep refrigerated and best consumed within 2 months. Keep out of reach of children.

Precaution: If you are nursing, pregnant, taking medication or have a medical condition, you should consult your health care specialist prior to using this product.

Halal-certified.

Made in USA.

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   Thomas Aigner, et al, Virchows Archiv B Cell Pathol (1992) 62:337-345 
    
2. Oral administration of type-II collagen peptide 250-270 suppresses specific cellular and humoral immune response in collagen-induced arthritis 
   
   Ping Zhu, Xiao-Yan Li, Hong-Kun Wang, Jun-Feng Jia, Zhao-Hui Zheng, Jin Ding, Chun-Mei Fan, Clinical Immunology (2007) 122,75-84 
    
3. Boswellic acids in chronic inflammatory diseases. 
   
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4. Boswellia serrata: An overall assessment of in Vitro, Preclinical, Pharmacokinetic and Clinical Data 
   
   Mona Abdel-Tawab, Oliver Werz and Manfred Schubert- Zsilavecz, Clin Pharmacokinet 2011;50 (6): 349 – 369 
    
5. A double blind, randomized, placebo controlled study of the efficacy and safety of 5-LoxinR for treatment of osteoarthritis of the knee 
   
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6. Ist H15 (Harzextrakt von Boswellia serrata, “Weihrauch”) eine sinnvolle Erganzung zur etablierten medikamentosen Therapie der chronischen Polyarthritis?–Ergebnisse einer doppelblinden Pilotstudie. 
   
   [Is H15 (resin extract of Boswellia serrata, “incense”) an efficient supplementation to established drug therapy in RA? – Results of a double blinded pilot trial] 
   
   Sander O, Herborn G, Rau R. Z Rheumatol. 1998 Feb; 57(1): 11-6. 
    
7. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee –A randomized double blind placebo controlled trial 
   
   N. Kimmatkar, V. Thawani, L. Hingorani, and R. Khiyani; Phytomedicine 10: 3–7 (2003) 
    
8. Special extract of BOSWELLIA serrata (H 15) in the treatment of rheumatoid arthritis 
   
   Etzel R. Phytomedicine. 1996 May;3(1):91-4. 
    
9. Effects of Oral Administration of Type II Collagen on Rheumatoid Arthritis 
   
   David E. Trentham, et al, Science, New Series, Vol. 261, No. 5129 (Sep. 24, 1993), pp. 1727-1730 
    
10. Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial 
    
    David C. Crowley, et al, Int J Med Sci 2009; 6(6):312-321. 
     
11. Effect of Intra-articular Injection of Hyaluronic Acid in Rheumatoid Arthritis Patients with Knee Osteoarthritis 
    
    Chen-Liang Chou, et al, J Chin Med Assoc2008; 71(8):411–415 
     
12. Efficacy of intra-articular hyaluronic acid in patients with osteoarthritis of the ankle: a prospective study 
    
    Dr Shu-Fen Sun M.D., et al, OsteoArthritis and Cartilage (2006) 14, 867 874 
     
13. Effectiveness of intra-articular hyaluronic acid for ankle osteoarthritis treatment: a systematic review and meta-analysis. 
    
    Chang KV, et al, Arch Phys Med Rehabil. 2013 May;94(5):951-60. 
     
14. Intra-articular Hyaluronic Acid Potential Treatment of Younger Patients with Knee Injury andor Post-Traumatic Arthritis 
    
    Jazrawi LM, Rosen J. The Physician and Sportsmedicine, 2011 May; 39(2):107-13. 
     
15. Relationship between serum hyaluronic acid level and disease activity in early rheumatoid arthritis 
    
    M Majeed, F McQueen, S Yeoman, L McLean, Ann Rheum Dis 2004; 63:1166–1168. 
     
16. Reduced pain from osteoarthritis in hip joint or knee joint during treatment with calcium ascorbate. A randomized, placebo-controlled cross-over trial in general practice 
    
    Hertz Jensen N. Ugeskr Laeger 2003;165:2563–6 
     
17. Glucosamine Sulfate Use and Delay of Progression of Knee Osteoarthritis 
    
    Pavelka K, et al, Arch Intern Med. 2002 Oct 14;162(18):2113-23. 
     
18. Glucosamine sulfate reduces osteoarthritis progression in postmenopausal women with knee osteoarthritis evidence from two 3-year studies 
    
    Bruyere O, et al, Menopause: The Journal of The North American Menopause Society Vol. 11, No. 2, pp. 138–143 
     
19. Evaluation of the lipoxygenase inhibitory effect of boswellic acid analogues 
    
    Dr.P.R Sudhakaran, Manju devi.S 

20. Glucosamine Sulfate Use and Delay of Progression of Knee Osteoarthritis: a 3-year, randomized, placebo-controlled, double-blind study

    Pavelka et al. (2002). Archives of internal medicine, 162(18):2113-23. doi: 10.1001/archinte.162.18.2113.

21. Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial

    Kim, Axelrod et al. (2006). Osteoarthritis and Cartilage, 14(3): 286-294.

22. Effects of diet type and supplementation of glucosamine, chondroitin, and MSM on body composition, functional status, and markers of health in women with knee osteoarthritis initiating a resistance-based exercise and weight loss program

    Magrans-Courtney et al. (2011). Journal of the International Society of Sports Nutrition, 8(8).

23. Glucosamine and Chondroitin Sulfate as Therapeutic Agents for Knee and Hip Osteoarthritis

    Bruyere & Reginster (2007). Drugs & Aging, 24:573–580